PDF Compilation of Adverse Drug reaction

 

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Aplastic Anemia
Antibiotics

•      Chloramphenicol

•      Cotrimoxazole

•      Nitroforantoin

 

Antirheumatic

•      Gold salts

•        D penicillamine

Antithyroid

•      Carbimazole

•      Methimazole

•        Methylthiouracil

Antiinflammatory

•      Phenylbutazone

•      Indomethacin

•        Diclofenac

Cytotoxic drugs

•      Vincristine

•      Adriamycin

•      Methotrexate

•        Chlorambucil

Psychotropic

•      Phenothiazine

 

Anticonvulsant

•        Phenytoin (alpha methyl hydantoin)

 

Others

•      Zidovudin

•      Felbamate

•      Colchicine

•        Trimethadione

 

 

MegaloblasticAnemia
 

•      Methotrexate

•      Phenytoin

•      Cytosine arabinoside

•      Phenobarbitone

 

 

 

•      Pentamidine

•      Pyrimethamine

•        Zidovudine

•        Sulfasalazine

•        5-Fluorouracil

 

 

•      Triamterene

•      Primidone

•      Azathioprine

•      Trimethoprim

 

 

 

 

 

Cardiomyopathy
 

•      Daunorubicin

•      Emetine

•        Lithium

 

•      Phenothiazines

•      Trastuzumab

 

 

•      Sympathomimetics

•        Doxorubicin (Adriamycin)

 

Hyperpigmentation
 

•      Amiodarone

•      Oral contraceptives

•      Cyclophosphamide

•      Vitamin A

 

 

•      Busulfan

•      Minocyclines

•      Corticotropin

•        Bleomycin

 

•      Phenothiazines

•      Gold salts

•      Chloroquine

•        Clofazimine

 

 

Hyperpigmentation
 

•      Amiodarone

•        Oral contraceptives

•        Cyclophosphamide

•        Busulfan

 

•        Vitamin A

•        Minocyclines

•      Corticotropin

•        Bleomycin

 

•      Phenothiazines

•        Gold salts

•        Chloroquine

•      Clofazimine

 

 

Gynaecomastia
 

•        Calcium channel antagonist

•        Digitalis

•        Phenytoin

•        Griseofulvin

•        Isoniazide

•        Methyldopa

 

 

•        Spironolactone

•        Reserpine

•        Estrogens

•        Ethionamide

•        Cyprotenrone acetate

•        Clomiphene

 

 

•        Testosterone

•        Griseofulvin

•      Ketoconazole

•        Flutamide

•        Goserelin

•        Cimetidine

 

 

 

 

 

Hyperprolactinemia and galactorrhea
•        Estrogens

•        Phenothiazines (chlorpromazine)

•        Butyrophenones(haloperidol)

•        Opiates

•        Fluoxetine

 

•        Alpha methylodopa

•        Reserpine

•        Verapamil

•        Amitriptyline, amoxapine

 

•        Thioxanthenes

•        Antiestrogen

•        Metoclopramide

•        Cimetidine

•        Ranitidine

 

 

Precipitation of Asthma
 

•        NSAIDs

•        Beta blockers

•        Heparin

 

•        Opioids

•        Heparin

•        Disulfiram

 

•        Nitrofurantoin

•        Organophosphates

 

Diarrhea
 

•        Broad spectrum antibiotics

•        Clindamycin

•        Cocaine

•        Colchicine

•        Digitalis

 

 

•        Magnesium antacids

•        Donepezil

•        Guanethidine

•        Lactose

•        Lincomycine

•        Mesoprostol

 

 

•        OCP

•        Purgative

•        Reserpine

•        Ticlopidine

•        Methyl dopa

 

 

Constipation
 

•        Aluminium Hydroxide

•        Barium sulphate

•        Phenothiazines

•        Ion exchange resins

 

 

•        Opiates

•        Tricyclic antidepresants

•        Verapamil

 

 

•        Ferrous sulphate

•        Calcium carbonate

•        Ganglionic blockers

 

 

 

 

Hypertension
 

•        Cocaine

•        Tricyclic antidepressants

•        Erythropoietin

•        MAO inhibitors

 

•        Cyclosporine

•        Valdecoxib (NSAID)

•        Oral contraceptives

•        Glucocorticoids

 

 

•        Sympathomimetics

•        Clonidine withdrawl

•        Rofecoxib (NSAID)

 

 

Hypotension
 

•       Theophylline

•       Bretylium

•       Quinidine

•       Chlorpromazine

•       Calcium channel

•       Adenosine

 

 

•       Morphine

•       Glyceryl trinitrate

•    Amiodarone

•       Clonidine

•       Guanethidine

•       Alpha blockers

 

•       Fosphenytoin (I.V.)

•       Diuretics

•       Levo-dopa

•       Blockers

•        IL-2

•       β-blockers (I.V.)

 

First dose hypotension (First dose phenomenon)
 

•       Prazosin

•       Murumonab CD3

 

•       Sargramostim

 

•       ACE inhibitors Captopril)

 

CHF
 

•       Minoxidil

•       Phenylbutazone

•       Estrogens

•       Indomethacin

 

•       β – blockers

•       Verapamil

•       Mannitol

•       Carbenoxolone sodium

 

•       Diazoxide

•       CCBs

•       Corticosteroids

 

 

 

 

 

Precepitation of MI or exacerbation of angina
 

·         Amphetamines

·         Dipyridamol

·         Excessive thyroxine

·         Nifedipine

·         Theophylline

·         Minoxidil

 

·         Alpha blocker

·         Vasopressin

·         Hydralazine

·         Nicotine and cocaine

·         Beta agonists

·         Sumatriptan

 

·         Ergotamine

·         Methysergide

·         Oxytocin

·         Beta blockers withdrawal

·         Decongestants

 

Depression
 

·         Anticonvulsants

·         Bromocriptine

·         Fluoroquinolones

·         Levodopa

·         Opioides

 

·         β – blockers

·         Disulfiram

·         Statins

·         Estrogen (OCPs)

 

·         Benzodiazepines

·         Interferon- α

·         Barbiturates

·         Calcium channel blockers

 

Seizures
 

·         β Lactam antibiotics

·         Quinolones

·         Acyclovir & Ganciclovir

·         Isoniazid

·         Meperidine

·         Tramadol

·         Pethidine

·         Flumazanil

·         Cocaine

 

·         Local anaesthetics

·         Cyclosporine

·         OKT3

·         Tacrolimus

·         Interferons

·         Antidepressants

·         Nalidixic acid

·         Amphetamine

·         Phencyclidine

 

·         Antipsychotics

·         Lithium

·         Theophylline

·         Alcohol withdrawl

·         Barbiturate withdrawl

·         Benzodiazepine withdrawl

·         Physostigmine (iv)

·         Methyphenidate

·         Vincristine

 

 

 

 

Extrapyramidal symptoms
 

·         Butyrophenones (Haloperidol)

·         Levodopa

·         Reserpine

 

·         Methyldopa

·         Metoclopromide

·         Tricyclic Antidepressants

 

·         OCP ‘S

·         Phenothiazines

 

Sedation
 

·         Clonidine

·         Methyldopa

·         TCAs

 

·         Anthistaminics

·         Barbiturates

 

·         Benzodiazepines

·         Reserpine

 

Tremers
 

·         TCAs

·         Theophylline

 

·         Lithium

 

·         Sympathomimetics (β2 -agonists)

 

Hypokalemia
 

·         β agonist

·         Steroids

·         Vitamin B12

·         Amphotericin B

·         Gentamicin

 

·         Licorice

·         α Blockers

·         Diuretics

·         Lithium(AI13)

·         Theophylline

 

·         Penicillin derivatives

·         Toluene abuse

·         Carbenoxalone

·         Insulin

·         CA inhibitors

 

Hyperkalemia
 

·         ACE inhibitors

·         Heparin

·         ARBs (angiotensin antagonists)

 

·         Trimethoprim

·         NSAIDS

·         Succinylcholine

·         Pentamidine

 

·         Digoxin toxicity

·         K+ sparing diuretic

·         Cyclosporine

·         β -blockers (initially)

 

 

Hyperuricemia (gout)
 

·         Pyrazinamide

·         Ethambutol

·         Diuretics

·         Cyclosporine

 

·         Alcohol

·         Levodopa

·         Nicotinic acid

 

·         Chlorthalidone

·         Cytotoxic drugs

·         Aspirin (Low dose)

 

Hypoglycemia
 

·         Insulin

·         Sulfonylureas

·         ACE inhibitors

 

·         Ethanol

·         Pentamidine

·         Octreotide

 

·         Quinine

·         Sulfonamide

·         Salicylates

 

Hyperglycemia
 

·         Asparaginase

·         Chlorthalidone

·         Diazoxide

·         Encainide

·         Thyroid hormones

·         Glucagon

·         L-Asparaginase

·         β -adrenergic agonists

·         β -blockers (propranolol)

 

·         Ethacrinic acid

·         Frusemide

·         Glucocorticoids

·         Growth-hormone

·         Vacor

·         Cyclosporine

·         HIV protease inhibitors

·         α -IFN

 

·         Niacin

·         OCP

·         Phenytoin

·         Clozapine

·         Tacrolimus

·         Pentamidine

·         Thiazides

·         Protease inhibitors

 

Hypocalcemia
 

·         Calcitonin

·         Plicamycin

 

·         Gallium nitrate

·         Bisphosphonates

 

·         Phenytoin

 

 

 

Hypercalcemia
 

·         Cholecalciferol

 

·         Calcium(IV)

 

·         Thiazides

 

Hypertriglyceridemia
 

·         Estrogen

·         Glucocorticoids

·         Furosemide

·         OCPs

 

·         Retinoic acid

·         Bile acid – binding resin

·         Thiazides

 

·         HIV protease inhibitors

·         Ethanol

·         β – blockers

 

Hypercholesterolemia
 

·         Thiazide

 

·         Tegretol

 

·         Cyclosporine

 

Hemolysis in G-6-PD deficiency
 

·         Aminosalicylicacid

·         Sulfonamides (Sulfamethoxazole)

·         Nitrofurantoin

·         Analgesics – Aspirin, Acetanilid

·         Vitamin K (water soluble form)

·         Probenecid

·         Cotrimoxazole

·         Niridazole – Phenazopyridine

·         Quinidine

 

·         Nalidixic acid

·         Antimalarials — Primaquine, Quinine, Chloroquine (sometimes)

·         Vitamin C

·         Phenacetin

·         Chloramphenicol

·         Methylene blue

·         Procainamide

·         Dapsone

·         Doxorubicin

 

Hemolyticanemia (even without deficiency of G-6-PD)
 

·         Isoniazid

·         Rifampicin

·         Sulfonamide

 

·         Quinidine

·         Procainamide

·         Penicillin

 

·         Phenacetin

·         Dapsone

·         Melphalan

 

Dysguesia (Altered taste sensations)
 

·         Acetazolamide

·         Biguanide

·         Captopril

 

·         Griseofulvin

·         Lithium

·         Metronidazole

 

·         Penicillamine

·         Rifampin

 

Metallic taste
 

·         Antibiotics – Metronidazole

·         Anticancer – cisplatin, dacarbazine

·         Anti-arrhythmatics-amiodarone, adenosine

 

·         Disulfiram

·         Antidiabetics-phenformin

·         TCA-Nortryptiline

·         Anticonvulsants

 

 

·         Acetazolamide

·         Antithyroid drugs

·         Gold

·         Vincristine

 

Gingival hyperplasia
 

·         Phenytoin

·         Calcium antagonists

 

·         Sirolimus

·         Lamotrigine

 

·         Cyclosporine

 

Methemoglobinemia
 

·         Aniline and its derivatives

·         Aminophenols

·         Aminophenones

·         Chlorates

·         Dapsone

·         Local anaesthetics – Prilocaine, Benzocaine

·         Nitrites

 

·         Naphthalene

·         Nitrates (Nitroglycerine is included in nitrates)

·         Nitrobenzenes and related compounds

·         Oxides of Nitrogen

·         Phenazopyridine

·         Primaquine and related antimalarials

·         Sulfonamides

 

 

 

Pseudotumorcerebri (Increased ICT)
 

·         Amiodarone

·         Glucocorticoids (withdrawl)

·         Quinolones

 

·         Mineralocorticoids (withdrawl)

·         Hypervitaminosis A

·         Nalidixic acid

 

·         Oral contraceptives

·         Tetracyclines

·         Sympathomimetics

 

Peripheral neuropathy
 

·         Amiodarone

·         Chloramphenicol

·         Chloroquine

·         Cisplatin

·         Clioguinol

·         Clofibrate

·         Zalcitabine

·         Procarbazine

·         Polymyxin, colistin

 

·         Demeclocycline

·         Disopyramide

·         Ethambutol

·         Ethionamide

·         Glutethemide

·         Hydralazine

·         Isoniazid

·         Didanosine

·         Paclitaxol

 

·         Mustine

·         Nalidixic acid

·         Nitrofurantoin

·         Perhexiline

·         Phenelzine

·         Phenytoin

·         Streptomycin

·         Stavudine

 

 

Predominant sensory neuropathy
 

·         Cisplatin

·         Hydralazine

·         Metronidazole

 

·         Misonidazole

·         Pyridoxine

·         Taxol

 

·         Vincristine

·         Nucleoside analogues (Dinanosine, Stavudine)

 

Predominant motor neuropathv
·         Dapsone ·         Suramine ·         Lead

 

 

 

 

Pulmonary fibrosis (pulmonary infiltrate or interstitial lung disease)
 

·         Acyclovir

·         Amiodarone

·         Bleomycin

·         Methotrexate

·         Busulphan

·         Carmustine

 

·         Chlorambucil

·         Vinblastin

·         Cyclophosphamide

·         Nitrofurantoin

·         Procarbazine

·         Gold

 

·         Melphalan

·         Methysergide

·         MitomycinC

·         Sulfonamides

·         Penicillamine

 

Myopathy
 

·         Clofibrate

·         Zidovudine

·         Amphotericin-B

·         Gemfibrozil

·         Statin

·         Cimetidine

 

·         Glucocorticoids

·         Cyclosporine

·         Chloroquine

·         OCPs

·         Spironolactone

 

·         Acetazolamide

·         Danazol

·         D penicillamine

·         Daptomycine

·         Gold

 

Lactic acidosis
 

·         Phenformin

·         Metformin

·         Zidovudine

 

·         Zalcitabine

·         Spironolactone

 

·         Acetazolamide

·         Salicylates

 

Hypothyroidism
 

·         Lithium

·         Amiodarone

·         Iodides

·         Ethionamide

·         Carbamazepine

 

·         Sulfonamide

·         Paraminosalycylic acid (PAS)

·         Carbimazole

·         Phenylbutazone

 

·         Phenobarbitone

·         Rifampicin

·         Acetazolamide

·         Phenytoin

 

 

 

Hyperthyroidism
·         Amiodarone ·         Iodides

 

Ototoxicity
A) Vestibular (primarily

·         Aminoglycosides

·         Mustine

·         Quinidine

·         Quinine

·         Chloroquine

·         Vancomycin

·         Furosemide

·         Ethacrynic acid

·         Salicylates (high dose)

B) Auditory (primarily)

·         NSAIDs

·         Ethacrynic acid

·         Vancomycin

·         Aminoglycosides

·         Cisplatin

 

Deafness
 

·         Aminoglycosides

·         Aspirin

·         Bleomycin

·         Chloroquine

·         Cidofovir

 

·         Cisplatin

·         Quinine

·         Erythromycin

·         Ethacrynic acid

 

·         Furosemide

·         Interferon

·         Mustine hydrochloride

·         Deferoxamine

 

Optic neuritis
 

·         Aminosalicylic acid

·         Amiodarone

·         Isoniazid

·         Phenylbutazone

 

·         Streptomycin

·         Quinine

·         Penicillamine

 

·         Chloramphenicol

·         Ethambutol

·         Phenothiazines

 

 

 

Disturbed color vision
 

·         Sulfonamides

·         Thiazides

·         Barbiturates

 

·         Digitalis

·         Ethambutol

 

·         Quinine

·         Streptomycin

 

Precipitation of glaucoma
 

·         Mydriatics

·         Synpathomimetics

 

·         TCAs

 

·         Corticosteroids

 

Addison’s disease (Medical adrenalectomy)
 

·         Metyrapone

·         Aninoglutethimide

 

·         Cytotoxic drugs (mitotane)

 

·         Ketoconazole

 

Osteoporosis
 

·         Glucocorticoids

·         Cyclosporine

·         Cytotoxic drugs

·         Anticonvulsants

 

·         Excessive alcohol intake

·         Aluminum

·         Excessive thyroxine

 

·         GnRH agonist

·         Heparin

·         Lithium

 

SLE (antinuclear antibodies)
 

·         Antiarrhythmics : Procainamide, disopyramide, propafenome, quinidine

·         Anti-hypertensives : hydralazine, methyldopa

·         ACE inhibitors

·         Beta-blockers

·         Antithyroid-propylthiouracil, iodides

·         Antipsychotics – Chlorpromazine, lithium

 

·         Anti-convulsauts : Carbamazepine, phenytoin

·         Antibiotic : Isoniazid, minocycline, macrodantin, sulphonamide

·         Antirheumatic : Sulfasalazine

·         Diuretics : Hydroclorothiazide

·         Statins : Lovastatin, simvastatin

·         Biologics : IFN, TNF-a inhibitors

·         Anticancer : Bleomycin, asparginase

 

Hirsutism
Androgenic drugs Non – androgenic drugs
 

·         Acetazolamide

·         Anabolic steroids

·         Androgenic progestins(Norethisterone)

·         Dihydroepiandrosterone

 

·         Testosterone

·         Danazole

·         Corticotropin

·         Metyrapone

 

·         Phenytoin

·         Penicillamine

·         Triamterene – hydrochlorthiazide

·         Cyclosporine

 

·         Minoxidil

·         Penicillamine

·         Phenothiazines

 

Hypertrichosis
 

·         Phenytoin

·         Streptomycin

·         Acetazolamide

·         Interferon

 

·         Diazoxide

·         Corticosteroids

·         Cyclosporine

 

·         Psorelin

·         Latanoprost

·         Minoxidil

 

Decreased libibo(impotence)
 

·         β – blockers

·         Antipsychotics

·         Lithium

 

·         Clonidine

·         Diuretics

·         Methyldopa

 

·         Oral contraceptives

·         Sedatives

·         TCAs

 

Pericarditis
 

·         Procainamide

·         Isoniazid

·         Phenytoin

 

·         Anticoagulants

·         Methysergide

 

·         Minoxidil

·         Hydralazine

 

Cholestatic jaundice
 

·         Methyl testosterone

·         Sulindac

·         Methimazole

·         Chlorpropamide

·         Nitrofurantoin

·         Nifedipine, verapamil

 

·         Erythromycin, Nitrofurantoin, Rifampin

·         Amoxicillin -clavulanic acid, oxacillin

·         Norethynodrel with mestranol

 

·         Chlorpromazine

·         Methimazole

·         Anabolic steroids, busulfan, tamoxifen

·         Cyclosporine

·         Gold salts

 

Pancreatitis
 

·         Asparaginase

·         Corticosteroids

·         Didanosine

·         Opioids

·         Stavudine

·         Oral contraceptives

 

·         Thiazides

·         Zalcitabine

·         Estrogens

·         Azathioprine

·         Mercaptopurine

 

·         Ethacrynic acid

·         Pentamidine

·         Sulfonamides

·         Valproic acid

·         Furosemide

 

Pulmonary eosinophilia
 

·         Amiodarone

·         Carbamazepine

·         Gold salts

·         Nilutamide

·         Captopril

·         Phenytoin

 

·         Sulfasalazine

·         Nitrofurantoin

·         Penicillamine

·         GM-CSF

·         Propylthiouracil

·         Bleomycin

 

·         L-tryptophan

·         Minocycline

·         Contrast media

·         Methotrexate

·         Iodine

·         Aspirin

Acute tubular necrosis
 

·         Aminoglycosides

·         Amphotericin B

·         Cephaloridine

·         Cisplatin

·         Colistin

 

·         Cyclosporine

·         Intravenous immune globulin

·         Methoxyfluranes

·         Polymyxin

 

·         Radioiodinatedcontrast medium

·         Sulfonamides

·         Tetracyclines

·         Acetaminophen

 

Interstitial nephritis
 

·         Cephalosporine

·         Rifampcin

·         NSAIDS

·         Allopurinol

 

·         Penicillins (esp. methicillin)

·         Furosemide

·         Phenindione

 

·         Ciprofloxacin

·         Thiazides

·         Sulphonamides

 

Urine disolouration
 

·         Chloroquine

·         Iron salts

·         Levodopa

·         Methyldopa

·         Metronidazole

·         Naphthalene

·         Nitrofurantoin

·         Phenacetin

·         Aminopyrine

·         Phenolphthalein

 

·         Quinine

·         Sulfonamides

·         Anthraquinone

·         Methylene blue

·         Triamterene

·         Amitriptyline

·         Primaquine

·         Rifampin

·         Daunorubicin

·         Doxorubicin

 

·         Aminosalicylic acid

·         Indomethacin

·         Chlorzoxazone

·         Heparin

·         Phenazopyridine

·         Phenindione

·         Sulfasalazine

·         Warfarin

·         Riboflavin

 

Thrombocytopenia
 

·         Thiazides

·         Cytarabine

·         Carbamazepine

·         Aspirin

·         Quinine

·         Methotrexate

 

·         Chloroquine

·         Busulfan

·         Gold salts

·         Daunorubicin

·         PAS

·         Sulfonamides

 

·         Ethanol

·         6-mercaptopurine

·         Chlorpropamide

·         Cycophosphamide

·         Methyldopa

·         Quinidine

 

 

 

 

Folate deficiency
Interference with folic acidabsorption Inhibition ofdihydrofolate reductase Impair folate metabolism
 

·         Phenytoin

·         Phenobarbitone

·         Primidone

·         Sulfasalazine

·         Cotrimoxazole

 

·         Methotrexate

·         Pyrimethamine

·         Triameterene

·         Pentamidine

·         Trimethoprim

 

·         Alcohol

 

Precipitating acute intermittent porphyria
 

·         Barbiturates

·         Oral contraceptives

·         Griseofulvin

 

·         Estrogen

·         Chlorpropramide

·         Phenytoin

 

·         Rifampicin

·         Sulfonamides

 

SAFE drugs in Porphyria
 

·         Narcotic analgesics

·         Aspirin

·         Acetaminophen

·         Atropine

·         Bupivacaine

 

·         Penicillin and derivatives

·         Streptomycin

·         Benzodiazepines

 

·         Glucocorticoids

·         Insulin

·         Muscle relaxants

·         Bromides

 

Peptic ulcer
 

·         NSAIDs (most common)

·         Bisphosphonates

·         Chemotherapy

 

·         Clopidogrel

·         Crack cocaine

·         Glucocorticoids

 

·         Mycophenolatemofetil

·         Potassium chloride

 

 

 

Syndrome of inappropriate AIH (SIADH)
 

·         Vasopressin or desmopressin

·         Vincristine or vinblastine

·         Phenothiazines

·         Monoamine oxidase inhibitors

 

·         Chlorpropamide

·         Carbamazepine

·         Cyclophosphamide

·         Serotonin reuptake inhibitors

 

·         Oxytocin, high dose

·         Nicotine

·         Tricyclic antidepressants

 

Aggravation of mvsthenia gravis
 

·         Aminoglycosides:- Streptomycin, kanamycin, tobramycin

·         Tetracyclines

·         Nondepolarizing muscle relaxants : Pancuronium, atracurium

·         Local anaesthetics : Procaine, xylocaine

·         Quinine derivatives : Quinine, quinidine, chloroquine

 

·         Quinolones Ciprofloxacin, levofloxacin, ofloxacin

·         Macrolides : Erythromycin, azithromycin

·         β-blockers : Propranolol,  atenolol

·         Antiarrhythmics : Procainamide, phenytoin

·         Miscellaneous : Penicillamine, magnesium, botulinum toxin

 

Drugs precipitating in urine and causing obstruction
 

·         Antiviral: Acyclovir, atazanavir, indinavir,

·         Sulfa drugs: Sulfasalazine, sulfadiazine, acetylsulfamethoxazole, acetylsulfasoxazole, acetylsulfaguanidine

·         Other: Triametrine, silicate, guatfensin, magnesium trisilicate, ciprofloxacin.

 

Disulfiram like reaction
 

·         Metronidazole

·         Cefamandole

·         Procarbazine

 

·         Cefotetan

·         Cefoperazone

 

·         Moxalactam

·         Chlorpropamide

 

Aggravation of mvsthenia gravis
 

·         Antiarrhythmics

·         Antimicrobials

 

·         A ntihistaminics

·         Antidepressants

·         A ntipsychotics

·         Prokinetic

 

: Quinidine, procainamide, disopyramide, propafenone, amiodarone

: Quinine, mefloquine, artemisinin, halofantrine, sparfloxacin, gatifloxacin

: Terfenadine, astemizole, ebastine

: Amitryptyline and other tricyclics

: Thioridazine, risperidone

: Cisapride

 

Erythema muliforme (SJS/TEN)
 

·         Sulphones

·         Quinolones

·         Ethosuximide

·         Salicylates

·         Tocainide

·         Phynylbutazone

 

·         Cephalosporins

·         Valproic acid

·         Nalidixic acid

·         Codeine

·         Chlorpropamide

 

·         Tetracyclines

·         Piroxicam

·         Lamotrigine

·         Allopurinol

·         Penicillins

 

Exanthematousreaction
 

·         Penicillins (ampicillin)

·         Sulfonamides

·         Diuretics

·         INH

 

·         Phenytoin

·         Carbamezapine

·         Barbiturates

·         Phenylbutazone

 

·         Lamotrigine (Nevirapine)

·         Allopurinol

·         Rifampicin

Serum sickness like drug reaction (SSLDR)
 

·         Cefclor

·         Sulfonamides

·         Thiouracil

·         Ciprofloxacin

 

·         Penicillins

·         Barbiturates

·         Allopurinol

·         Propranolol

 

·         Tetracyclines

·         Carbamazepine

·         NSAIDs

 

Granuloma in liver
 

·         Phenylbutazone

·         Sulfonamides

 

·         Allopurinol

·         Quinidine

 

·         Diltiazem

·         Carbamazepine

 

Cytotoxic drugs causing mucositis
 

·         Bleomycin

·         Methotrexate

·         Amasacrine

·         Actinomycin-D

 

·         Paclitaxel

·         Hydroxyurea

·         Daunorubicin

·         Mithramycin

 

·         Cytosine arabinoside

·         Fluorouracil

·         Etoposide

·         Topotecan

 

Photosensitivity
a) Phototoxic

·         Tetracyclines

·         Nalidixic acid

·         Phenothiazines

·         Sulfonamides

·         Thiazides

·         Fluroquinolones

·         Amiodaroneom

b) Photoallergy

·         Sulfonamide

·         Chloroquine

·         Sulfonylureas

·         Chlorpromazine

·         Griseofulvin