- Rhinoscleroma is a progressive granulomatous disease of the upper respiratory tract.
- It is caused by the gram-negative coccobacillus K rhinoscleromatis or Frish Bacillus.
- The disease probably begins in areas of epithelial transition such as the vestibule of the nose, the subglottic area of the larynx, or the area between the nasopharynx and oropharynx.
- It is a chronic infection of the nose characterised by sclerosis and stenosis of the nasal passage.
- Rhinoscleroma may be found in all age groups, but typically young adults 20–30 years old are most frequently affected.
- Both sexes are equally affected.
- The disease is endemic in several parts of world.
- In India, it is seen more often in northern than in the southern parts.
- Airborne transmission combined with poor hygiene, crowded living conditions, and poor nutrition contributes to its spread.
PATHOLOGY OF RHINOSLEROMA
- The disease is characterized by presence of granulations which infiltrate the submucosa ,with scattered Mikulicz cells(large vacuolated foamy cells containing a central nucleus and acid fast Frisch bacilli),Rusell bodies(resmbling plasma cells with an eccentric nucleus and deep eosin staining cytoplasm) and lymphocytes in dense fibrous tissue.
CLINICAL FEATURES IN A CASE OF RHINOSCLEROMA
- Blocking of the nose,Nasal Discharge,Headache,Epistaxis
- External nose is firm and woody to touch.
- Anterior Rhinoscopy:
- 3 stages:
- Atrophic Stage:is present initially,with crusting ,roomy cavity and atrophic dry nasal mucosa.
- Nodular stage:Bluish red non-ulcerative polypoidal masses of rubbery consistency are formed.
- Fibrotic stage of stenosis:of the nasal passages varying from partial obstruction to total atresia .
- Throat:may show extension of the sclerosing process downwards from the nose to the oropharynx,larynx.
TREATMENT IN A CASE OF RHINOSCLEROMA
- In rhinoscleromatosis, organism may be difficult to eradicate, despite aggressive therapy.Relapses may occur.
- A combination of conservative surgical debridement and long-term antibiotic coverage is the mainstay of therapy for rhinoscleroma.
- Tetracycline has been shown to be effective.
- Fluoroquinolones may be used as an alternative, given their excellent gram-negative activity and convenient dosing regimen
- Mikulicz cells and Russell bodies are seen in Rhinoscleroma.
- A roomy nasal cavity and atrophic dry nasal mucosa with thick crust formation and woody hard external nose is seen in Rhinoscleroma.
- Rhinoscleroma is caused by Klebsiella Rhinoscleromatis.
- Rhinoscleroma is a slowly progressing granulomatous disease.
- Rhinoscleroma is most common in young adults 20–30 years old.
- Poor nutrition contributes to the spread of Rhinosleroma.
- Drug of choice in Rhinoscleromatosis is Tetracycline.
- Frish bacillus causes Rhinoscleroma.
Don’t Forget to Take the Below Quiz Based on All Previous Year
Question of NBE /NEET / DNB
0 of 12 questions completed
You must specify an email address.
You have already completed the quiz before. Hence you can not start it again.
Quiz is loading...
You must sign in or sign up to start the quiz.
You have to finish following quiz, to start this quiz:
0 of 12 questions answered correctly
Time has elapsed
You have reached 0 of 0 points, (0)
Thanks for Taking the Quiz .
Join Us on Whats App to get notification on any new quiz uploaded
Whats App Your Name & College Name to +91 770 2266770
|Table is loading|
|No data available|
Rhinoscleroma occurs due to ‑CorrectIncorrect
Rhinoscleroma is caused by:CorrectIncorrect
Drug of choice in rhinoscleromatosis is:CorrectIncorrect
True about rhinoscleroma are all, EXCEPT:CorrectIncorrect
Frish bacillus causes:CorrectIncorrect
Atrophic dry nasal mucosa, extensive encrustations with woody’ hard external nose is suggestive ofCorrectIncorrect
Mikulicz cell and Russell bodies are characterisitic of:CorrectIncorrect
ENT examination of an old man shows roomy nasal cavities, crust formation and woody hard external nose; which are seen in:CorrectIncorrect
Histology of a specimen shows Mikulicz cells and Russell bodies. These are characteristic of:CorrectIncorrect
Large nasal cavity with thick crust formation internally and ‘woody’ feel of external nose is TRUE about?CorrectIncorrect
A roomy nasal cavity with thick crust formation and woody hard external nose is seen in?CorrectIncorrect
Mikulicz cells and Russell bodies are seen in _________CorrectIncorrect