Biochemistry Basics – 22082


A 40 yr old woman presents with progressive palmoplantar pigmentation. X-ray spine shows calcification of intervertebral discs. Adding Benedict’s reagent to urine, gives greenish brown precipitate and blue-black supernatant fluid. What is the diagnosis?

A. Phenylketonuria

B. Alkapt onuria

C. Tyrosinemia type-2

D. Argininosuccinic aciduria


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