Image Based Question – 65227

This patient came to clinic with this defect, it is in?

A. Methylation

B. Nucleotide Excision Repair

C. DNA replication

D. Protein folding

Show Answer

Correct Answer » B Explanation

This patient present feature of Xeroderma Pigmentosum

Ans. is ‘b’ i.e., Nucleotide Excision Repair

Exposure to UV rays damages DNA due to production of convalent linkages between adjacent pyrimidines. Normally the damaged DNA is repaired by excision and repair. In xeroderma pigmentosa the repair of UV damaged DNA is defective.