Question
Drug of choice for Case of Poisoning of Substance shown in Photograph is?
A. Physostigmine.
B. Flumazenil.
C. Protamine sulphate.
D. N-acetyl cysteine.
Show Answer
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Correct Answer ยป C
Explanation
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Ans:C. Protamine sulfate
Heparin Toxicity
- Heparin is blood thinner that is given to patients in order to prevent blood clot formation.
- The main function of heparin is to prevent the conversion of clotting factors to avoid the formation of blood clots.
- The main symptom of an heparin overdose is the occurrence of bleeding. The patient will experience GI bleeding,Nose Bleeding,petechia over skin
- Protamine sulfate has been given to counteract the anticoagulant effect of heparin.
- It binds to heparin to form a stable ion pair, which does not have anticoagulant ctivity.
- The ionic complex is then removed and broken down by the reticuloendothelial system.
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