B. Coat’s Disease
C. Congenital Cataract
D. Any of the above
Ans:D. Any of the above.
The condition shown in the picture above represents Leukocoria(White pupillary reflex)
- It is a white pupillary reflex produced by any intraocular abnormality that reflects incident light toward the observer.
- The common causes of leukocoria in a child are retinoblastoma, persistent hyperplastic primary vitreous, retinopathy of prematurity, Coats disease, toxocariasis, congenital cataract, phakomatoses, Norrie disease, and retinal dysplasia and detachment.
- Retinoblastoma is the most common intraocular tumor of childhood. It may be inherited or sporadic in nature and bilateral or unilateral in presentation, and it usually manifests by 13 to 18 months of age. Posterior chamber mass with calcification dominates the imaging findings.
- Persistent hyperplastic primary vitreous (PHPV): congenital developmental anomaly of the eye resulting from failure of the embryological, primary vitreous and hyaloid vasculature to regress, whereby the eye is shorter, develops a cataract, and may present with whitening of the pupil.
- Coats disease: a typically unilateral disease characterised by abnormal development of blood vessels behind the retina, leading to blood vessel abnormalities in the retina and retinal detachment to mimic retinoblastoma.
- Toxocara canis: an infectious disease of the eye associated with exposure to infected puppies, which causes a retinal lesion leading to retinal detachment.
- Retinopathy of prematurity (ROP): associated with low birth weight infants who receive supplemental oxygen in the period immediately after birth, it involves damage to the retinal tissue and may lead to retinal detachment.