A newborn suffering from an autosomal dominant condition,presented with the following condition as shown in the image.What is the most probable diagnosis?
A. Milroy’s edema.
B. Meige edema.
C. Lymphedema tarda.
D. Lymphedema praecox.
Ans:A. Milroy’s disease
- It is a genetic developmental disorder affecting the lymphatic system.
- There are three forms of hereditary lymphedema: congenital hereditary lymphedema or Milroy disease; lymphedema praecox or Meige disease; and lymphedema tarda.
- Hereditary lymphedema type IA (Milroy’s disease) is characterized by swelling (edema) that is present at or shortly after birth (congenital).The legs are most often affected.
- Additional complications sometimes associated with hereditary lymphedema type I include upslanting toenails, small warty growths on the affected areas (papillomatosis), abnormally large or prominent leg veins, and, in males, urethral abnormalities and the development of a fluid-filled sac along the spermatic cord of the scrotum (hydrocele).
- Hereditary lymphedema type II (Meige disease, lymphedema praecox) develops around puberty or shortly thereafter in most individuals. This is the most common type of primary lymphedema.
- Lymphedema tarda is defined as primary lymphedema occurring after the age of 35.
- Most cases of hereditary lymphedema type IA and type II are inherited as autosomal dominant traits.