A patient presented with chronic exertional Dyspnea.Lung shows the following features.Regarding this condition,from the following statements,which is not true?
A. Age at diagnosis is generally above 60 years
B. Cor pulmonale is frequent
C. Pink puffers
D. pO2 and pCO2 usually within normal limits due to compensatory hyperventilation
Ans:B. Cor pulmonale is frequent
- First: Sectioned lung showing air-filled sacs.
- Second:Panacinar (Panlobular) emphysema showing involvement of the entire lobules and whole of acinus
The patient is suffering from Emphysema.
- Grossly, the lungs are voluminous, pale with little blood.
- The edges of the lungs are rounded.
- Mild cases show dilatation of air spaces .Advanced cases show subpleural bullae and blebs bulging outwards from the surface of the lungs with rib markings between them.
- The bullae are air-filled cyst-like or bubble-like structures, larger than 1 cm in diameter.
- They are formed by the rupture of adjacent air spaces while blebs are the result of rupture of alveoli directly into the subpleural interstitial tissue and are the common cause of spontaneous pneumothorax. Microscopically, depending upon the type of emphysema, there is dilatation of air spaces and destruction of septal walls of part of acinus involved i.e. respiratory bronchioles, alveolar ducts and alveolar sacs.
- Changes of bronchitis may be present. Bullae and blebs when present show fibrosis and chronic inflammation of the walls.