Image Based Question – 69966

A patient presented with a nasal polypoidal mass.Histopathological examination shows the following features.What can be the most probable diagnosis?

A. Antrochoanal Polyp

B. Allergic Nasal Polyposis

C. Rhinosporidiosis

D. Rhinoscleromatosis

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Correct Answer » C Explanation

Ans:C. Rhinosporidiosis.

RHINOSPORIDIOSIS.

• Rhinosporidiosis is caused by a fungus, Rhinosporidium seeberi.

• Typically it occurs in a nasal polyp but may be found in other locations like nasopharynx, larynx and conjunctiva.

• The disease is common in India and Sri Lanka and sporadic in other parts of the world.

• Microscopically, besides the structure of inflammatory or allergic polyp, large number of organisms of the size of erythrocytes with chitinous wall are seen in the thickwalled sporangia.

• Each sporangium may contain a few thousand spores.

• On rupture of a sporangium, the spores are discharged into the submucosa or on to the surface of the mucosa.

• The intervening tissue consists of inflammatory granulation tissue (plasma cells, lymphocytes, histiocytes, neutrophils) while the overlying epithelium shows hyperplasia, focal thinning and occasional ulceration .