A. Nasal Squamous Cell Carcinoma
B. Inflammatory Nasal Polyp
C. Inverted Papilloma
D. Nasopharyngeal Angiofibroma
Ans:D. Nasopharyngeal Angiofibroma.
Image shows:Angiofibroma nose. There is admixture of thin-walled blood vessels and spindled stroma. The blood vessels are variable-sized,some having incomplete muscle coat and there is absence of elastic tissue. The stroma has stellate fibroblasts and mast cells.
- This is a peculiar tumour that occurs exclusively in adolescent males (10-20 years of age) suggesting the role of testosterone hormone in its production.
- Microscopically, the tumour is composed of 2 components as the name suggests—numerous small endothelium lined vascular spaces and the stromal cells which are myofibroblasts .
- The androgen-dependence of the tumour is confirmed by demonstration by immunostaining for androgen receptors in 75% cases.