Identify the below given image of a pathology affecting Arterial wall.
A. Hyaline Arteriosclerosis
B. Hyperplastic Arteriosclerosis
C. Senile Arteriosclerosis
D. Mönckeberg’s arteriosclerosis
Ans:D. Mönckeberg’s arteriosclerosis
MÖNCKEBERG’S ARTERIOSCLEROSIS (MEDIAL CALCIFIC SCLEROSIS)
- Mönckeberg’s arteriosclerosis is calcification of the media of large and medium-sized muscular arteries, especially of the extremities and of the genital tract, in persons past the age of 50.
- The condition occurs as an age-related degenerative process, and therefore, an example of dystrophic calcification.
- However, medial calcification also occurs in some pathological states like pseudoxanthoma elasticum and in idiopathic arterial calcification of infancy.
- Medial calcification is often an incidental finding in X-rays of the affected sites having muscular arteries.
- The deposition of calcium salts in the media produces pipestem-like rigid tubes without causing narrowing of the lumen.
- Microscopically, Mönckeberg’s arteriosclerosis is characterised by deposits of calcium salts in the media without associated inflammatory reaction while the intima and the adventitia are spared.