A. Mainstay of treatment is PUVA
B. May be associated with hypo/hyperthyroidism
C. Melanocytes are absent
D. All of the above
Ans:D. All of the above.
Vitiligo is shown in the image.
Vitiligo is a focal failure of pigmentation d/t genetically predisposed destruction of melanocytes by immunological mechanism. So a patch of vitiligo shows marked absence of melanocytes & melanin in epidermis .
Vitiligo is associated with the following autoimmune diseases :-
- Alopecia areata
- Diabetes mellitus
- Pernicious anemia
- Addison disease
- Multiple endocrinopathy syndrome
Long standing vitiligo with leucotrichia (depigmented hair), acrofacial lesions and lesion on resistant area are indicators of poor prognosis for therapy.
Treatment includes topical steroidse (for localized,