Question
Which of the following statement about this condition affecting the penis is true?

A. Commonest site is glans penis
B. Distant metastasis is rare.
C. Circumcision soon after birth confers immunity
D. All of the above
Show Answer
Correct Answer » D Explanation |
![]() |
Ans :D. All of the above.
Carcinoma of Penis is shown in the image.
CARCINOMA OF PENIS
- Circumcision soon after birth confers immunity against carcinoma penis
Risk Factors:
- The following as risk factors for penile cancer: human papillomavirus (hpv) infection, smoking, smegma, phimosis, balanoposthitis, condyloma acuminata/ penile warts, leukoplakia of glans, paget’s disease, treatment of psoriasis with uv light, age, erythroplasia of queyrat and aids.
Carcinoma in situ
- At glans penis: Paget’s disease of penis or Erythroplasia of Queryat
- At shaft: Bowen’s disease – Usually in those older than age 35 years
- Bowenoid papulosis
- In sexually active young adults
- Multiple, pigmented papular lesions
- Related to HPV type 16
- Histologically indistinguishable from Bowen’s disease
- Virtually never develops into invasive carcinoma
Clinical features
- In adults recent onset phimosis should raise the suspicion of carcinoma penis
- Inguinal node enlargement(60%) is the most common presentation
- Little or no pain
- Altered urinary stream
- Inguinal nodes may erode the skin and death may result from erosion of femoral or external iliac artery
Spread
- First to horizontal group of inguinal nodes and then external iliac nodes
- From glans to lymph node of Cloquet in the femoral canal
- Blood spread is rare.Distant metastasis is rare.
Investigations
- FNAC of lymph nodes (NO OPEN BIOPSY)
- Sentinel Lymph Node Biopsy (SLNB) – Cabana sentinel node is located above and medial to the junction of saphenous and femoral veins.