A patient came with itchy tense blisters on normal skin as well as over urticarial plaques, as shown in the image. What is the diagnosis?
A. Pemphigus vulgaris
B. Bullous pemphigoid
C. Linear I2A disease
D. Dermatitis herpetiformis
Ans: B. Bullous pemphigoid
(Ref Fitzpatrick 7/e p432-441; Rooks 8/e p40.27, 13.19, 10.12-10.28)
- Most likely diagnosis =Bullous pemphigoid.
|Histology||Subepidermal blister with eosinophil rich infiltrate in perivascular and vesicular sites.|
|Linear band of IgG and/or
C3 in epidermal
131 * 0301
|Clinical features||Large tense blisters on flexor surfaces and trunk.|