Which of the following layer contains abundant desmosomes?
Ans. C. C
Stratum spinosum or prickle cell layer contains abundant desmosomes marked with the legend ‘C’ in the image.
|Picture shows layers of epidermis|
- “The epidermis can be divided into a number of layers from deep to superficial as follows: basal layer (stratum basale), spinous or prickle cell layer (.stratum spinosum), granular layer (stratum granulosum), clear layer (stratum lucidum) and cornified layer (stratum corneum.”-
- “The prickle cell layer (stratum spinosum) consists of several layers of closely packed keratinocytes that interdigitate with each other by means of numerous cell surface projections. The cells are anchored to each other by desmosomes that provide tensile strength and cohesion to the layer. These suprabasal cells are committed to terminal differentiation and gradually move upwards towards the cornified layer as more cells are produced in the basal layer. When skin is processed for routine light microscopy, the cells tend to shrink away from each other except where they are joined by desmosomes, which gives them their characteristic spiny appearance. Prickle cell cytoplasm contains prominent bundles of keratin filaments, (mostly K1 and KIO keratin proteins) arranged concentrically around a euchromatic nucleus, and attached to the dense plaques qt. desmosomes. The cytoplasm also contains melanosomes, either singly or aggregated within membrane-bound organelles (compound melanosomes). Langerhans cells and the occasional associated lymphocyte are the only non-keratinocytes present in the prickle cell layer. “
|Layers of Epidermis|