Amelogenesis Imperfecta


Amelogenesis Imperfecta


Amelogenesis imperfecta basics & molecular genetic explained under 2 minutes 28 seconds

    • Disease caused by Primary defect in enamel. -Weinmann et al,1945
    • Can be autosomal dominant, autosomal recessive or X-Linked

Also known as

  • Hereditary enamel dysplasia
  • Hereditary brown enamel
  • Hereditary brown opalescent teeth
  • Alterations of genes involved in process of formation and maturation of enamel
  • Analysis of X-linked AI is closely linked to locus DXS85 at Xp22
  • Wiktop in 1988 classified into 4 major categories
  • Hypomaturation-hypoplastic with taurodontism
  • Enamel is smooth, tend to chip from dentin
  • Teeth appear like crown preparations
  • Normal shape.
  • Teeth color- Opaque white to brown
  • Radiodensity of dentin is similar to enamel
  • Enamel is smooth, thin and easily lost

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