Amelogenesis Imperfecta
Amelogenesis imperfecta basics & molecular genetic explained under 2 minutes 28 seconds
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- Disease caused by Primary defect in enamel. -Weinmann et al,1945
- Can be autosomal dominant, autosomal recessive or X-Linked
Also known as
- Hereditary enamel dysplasia
- Hereditary brown enamel
- Hereditary brown opalescent teeth
- Alterations of genes involved in process of formation and maturation of enamel
- Analysis of X-linked AI is closely linked to locus DXS85 at Xp22
- Wiktop in 1988 classified into 4 major categories
- Hypomaturation-hypoplastic with taurodontism
- Enamel is smooth, tend to chip from dentin
- Teeth appear like crown preparations
- Normal shape.
- Teeth color- Opaque white to brown
- Radiodensity of dentin is similar to enamel
- Enamel is smooth, thin and easily lost
