Antioxidant

Antioxidant


ANTIOXIDANT

  • Molecule that prevent oxidation of other molecule.
  • Oxidative stress produces free radical,contribute to diseases.
  • It is measured by  BAP Test and d-ROMs test.

NATURAL AND SYNTHETIC ANTIOXIDANT

Antioxidant Source
Vitamin C Citrus Fruits
Vitamin E Vegetable Oil
Polyphenolic (resveratol and Flavoniod) Fruits, Red wine, Tea,Choclate, Orgeno, Coffe, Olive oil,Soy
Careteniods (lycopene carotene, lutien) Fruits Vegetable egg
Synthetic Propylgallate, Butylated Hydroxyanisole, Butylated Hydroxytoulene, Tertiarbutylhydroquinone.

CLASSIFICATION OF ANTIOXIDANTS

  1. ANTIOXIDANT ENZYMES
    1. Catalase
    2. Glutathione peroxidase
    3. Glutathione reductase
    4. Super oxide dismutase(both Cu -Zn and Mn)
  2. METAL BINDING PROTIENS
    1. Ceruloplasmin
    2. Ferritin
    3. Lactoferrin
    4. Metallotheinein
    5. Transferrin
    6. Hemoglobib
    7. Myoglobin
  3. Bilirubin
  4. Caroteniod
    1. Beta Carotene
    2. Alpha carotene
    3. Lutien
    4. Lycopene
    5. Zeaxanthin
  5. Vitamins A,C,E,D
  6. Uric acids
  7. Thiols
  8. Other-Copper, Selenium,Zinc,Alpha lipoic acid,Glutathione

MECHANISM OF ACTION

  • Vit. E prevents peroxidation of membrane phosphor lipids
  • Vit.C reactivate oxygen and scavenges free radicals
  • Super oxide dismutase reduces superoxide.
  • Catalase and glutathione convert hydrogen peroxide.

 What are antioxidants used for?

  •  Antioxidants may play a role in the management or prevention –
  1. Some cancers
  2. Macular degeneration
  3. Alzheimer’s diseases
  4. Some arthritis-related conditions.
  • Destroys free radicals.
  • Promote growth of healthy cell.
  • Support immune system

ANTIOXIDATIVE STRESS

  • Strong reducing acid binds to deitary minerals(iron,zinc)
  • Prevent their absorbtion
  • Examples are oxalic acid, tannins and phytic acid, which are high in plant-based diets.
  • Nonpolar antioxidants such as eugenol have toxicity limits.
  • examples are oxalic acid, tannins and phytic acid, which are high in plant-based diets

Exam Important

ANTIOXIDANT

  • Molecule that prevent oxidation of other molecule.

NATURAL AND SYNTHETIC ANTIOXIDANT

Antioxidant Source
Vitamin C Citrus Fruits
Vitamin E Vegetable Oil
Polyphenolic (resveratol and Flavoniod) Fruits, Red wine, Tea,Choclate, Orgeno, Coffe, Olive oil,Soy
Careteniods (lycopene carotene, lutien) Fruits Vegetable egg
Synthetic Propylgallate, Butylated Hydroxyanisole, Butylated Hydroxytoulene, Tertiarbutylhydroquinone.

CLASSIFICATION OF ANTIOXIDANTS

  1. ANTIOXIDANT ENZYMES
    1. Catalase
    2. Glutathione peroxidase(selenium imp.component)
    3. Glutathione reductase
    4. Super oxide dismutase(both Cu -Zn and Mn)
  2. METAL BINDING PROTIENS
    1. Ceruloplasmin
    2. Ferritin
    3. Lactoferrin
    4. Metallotheinein
    5. Transferrin
    6. Hemoglobib
    7. Myoglobin
  3. Bilirubin
  4. Caroteniod
    1. Beta Carotene
    2. Alpha carotene
    3. Lutien
    4. Lycopene
    5. Zeaxanthin
  5. Vitamins A,C,E,D
  6. Uric acids
  7. Thiols
  8. Other-Copper, Selenium,Zinc,Alpha lipoic acid,Glutathione

MECHANISM OF ACTION

  • Vit. E prevents peroxidation of membrane phosphor lipids
  • Vit.C reactivate oxygen and scavenges free radicals
  • Super oxide dismutase reduces superoxide.
  • Catalase and glutathione convert hydrogen peroxide.
Don’t Forget to Solve all the previous Year Question asked on Antioxidant

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