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Kawasaki Disease

Kawasaki Disease


KAWASAKI DISEASE

  • Kawasaki disease is mucocutaneous lesions with an acute, febrile, multisystem disease of children.
  • Mucocutaneous lymph node syndrome
  • Children <5years are mostly effected.

 Clinical Manifestations-

  • Non Suppurative adenitis
  • Edema
  • Congested conjunctiva
  • Erythema of the oral cavity, lips and palms, strawberry tongue
  • Desquamative rash
  • Mainly affects coronary vessels, giant coronary artery aneurysms due to thrombosis
  • Myocardial infarction and death
  • Pericardits

 Diagnosis-

  • Thrombocytosis, leuckocytosis and elevated ESR
  • Anti endothelial antibiodies

 Treatment-

  • IV immunoglobulins
Exam Question
 
  • Kawasaki disease  is a Mucocutaneous lesions
  • Kawasaki disease is Associated with coronary artery aneurysm in up to 25% of untreated case 
  • Kawasaki disease is Seen in children
  • child with bilateral non purulent conjunctivitis and 4 enlarged cervical lymph nodes , Conjusted pharynx pharynx ,trunk covered with polymorphous rash and  palmar erythema and desquamation of finger tips with Bilateral pedal oedema is suggested to have Kawasaki disease
  • Pedal edema, Truncal rash & Pharyngeal congestion are the component of Kawasaki disease
  • Kawasaki disease is associated with  Erythema,Red eye,Rash, Posterior cervical lymphadenopathy & Conjuctivitis
  • child with fever, non-purulent conjunctivitis, rashes, cervical lymphadenopthy, hepatomegaly  eruptions on trunk proximal extremities, bilateral bulbar conjunctivitis without discharge and fissuring -crusting- red lipsand desquamation of fingers and toes showing coronary artery aneurysm on ECG  is the most likely diagnosed to have Kawasaki disease
  • Strawberry tongue, Pedal Edema & Cervical Lymphadenopathy  are clinical manifestation of Kawasaki disease
  • The type of arteritis which may lead to myocardial infarction in children is Kawasaki disease
  • Immunoglobulin are the treatment of choice for Kawasaki disease
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