Malignant Hyperthermia

Malignant Hyperthermia


MALIGNANT HYPERTHERMIA

  • Receptor responsible for malignant hyperthermia is Ryanodine receptor
  • Agent causing malignant hyperthermia is Succinylcholine
  • Hyperkalemia, Metabolic acidosis & Hypertension are seen in malignant hyperthermia 
  • Halothane,Lidocaine, Isoflurane & Suxamethonium trigger malignant hyperthermia
  • Sevoflurane is contraindicated for induction of anaesthesia in patient with H/O malignant hyperthermia
  • Increased muscle metabolism by excess of calcium ions causes increased heat production in malignant hyperthermia
  • Malignant hyperthermia is best treated with Dantrolene sodium
  • End-tidal CO2 is increased to maximum level in Malignant hyperthermia
  • Difference between thyrotoxicosis and malignant hyperthermia is Elevated serum CPK level in MH
  • Malignant hyperthermia is caused due to Increased intracellular Ca
Exam Question
 
  • Receptor responsible for malignant hyperthermia is Ryanodine receptor
  • Agent causing malignant hyperthermia is Succinylcholine
  • Hyperkalemia, Metabolic acidosis & Hypertension are seen in malignant hyperthermia 
  • Halothane,Lidocaine, Isoflurane & Suxamethonium trigger malignant hyperthermia
  • Sevoflurane is contraindicated for induction of anaesthesia in  patient with H/O malignant hyperthermia
  • Increased muscle metabolism by excess of calcium ions causes increased heat production in malignant hyperthermia
  • Malignant hyperthermia is best treated with Dantrolene sodium
  • End-tidal CO2 is increased to maximum level in Malignant hyperthermia
  • Difference between thyrotoxicosis and malignant hyperthermia is Elevated serum CPK level in MH
  • Malignant hyperthermia is caused due to Increased intracellular Ca
Don’t Forget to Solve all the previous Year Question asked on Malignant Hyperthermia

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