Portal vein
PORTAL VEIN
- The portal vein or hepatic portal vein is a blood vessel that carries blood from the gastrointestinal tract, Common Bile Duct, pancreas and spleen to the liver.
- Two capillary beds connected by a larger blood vessel characterizes a portal system of blood vessels
- This blood is rich in nutrients that have been extracted from food, and the liver processes these nutrients;
- It also filters toxins that may have been ingested with the food.
- 75% of total liver blood flow is through the portal vein, with the remainder coming from the hepatic artery proper.
- The blood leaves the liver to the heart in the hepatic veins.
- The portal vein is not a true vein, because it conducts blood to capillary beds in the liver and not directly to the heart.
- It is a major component of the hepatic portal system, one of only two portal venous systems in the body – with the hypophyseal portal system being the other.
- Whole system is valve less.
STRUCTURE:
- 8 cm (3 inches) in adults.
- Originating: behind the neck of the pancreas at L2 level.
- Situated: deep to the hepatic artery and cystic duct
- Formed by: the union of the superior mesenteric vein and the splenic vein.
- The portal vein is occasionally called the splenic-mesenteric confluence.
- There is stream line flow, i.e blood in superior mesenteric vein drains into right lobe of liver & blood in splenic vein drains into left lobe.
- Before entering the liver thgrough porta hepatis, portal vein divides into right & left bronchus.
- Right branch is shorter & wider, & after receiving cystic vein it enters the right lobe of liver.
- Left branch is longer & narrower, & just before entering the left lobe it receives:
- Paraumblical vein along with ligamentum teres (remnant of left umblical vein)
- Ligamentum venosum (remnant of ductus venosus)
- It ramifies further, forming smaller venous branches and ultimately portal venules.
- Each portal venule courses alongside a hepatic arteriole and the two vessels form the vascular components of the portal triad.
- These vessels ultimately empty into the hepatic sinusoids to supply blood to the liver.
Important relations about portal vein
- Portal vein passes behind 1st part of duodenum.
- It can be divided into:
1. Infraduodenal part
- Anterior :- Neck of pancreas
- Posterior :- IVC
2. Retroduodenal part
- Anterior :- Ist part of duodenum, bile duct, gastroduodenal artery
- Posterior :- IVC
3. Supraduodenal part
- Anterior :- Hepatic artery, bile duct
- Posterior :- IVC, separated by epiploic formen
TRIBUTARIES:
- Splenic vein
- Superior mesenteric vein
- Inferior mesenteric vein
- Gastric veins
- Cystic & Preumblical vein
- Superior pancreatico-duodenal
Portacaval anastomoses (Portosystemic communications)
- Tributaries of hepatic portal system anastomose with tributaries of systemic ciurculation, called portocaval anastomosis.
- In cases of portal hypertension these anastamoses may become engorged, dilated, or varicosed and subsequently rupture.
SITE OF PORTOCAVAL ANASTOMOSES |
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SITE |
PORTAL VEIN |
SYSTEMIC VEIN |
Lower end of esophagus |
Left gastric |
Oesophageal veins |
Umbilicus |
Paraumblical |
Above: Superior epigastric, lateral thoracic Below: Superior epigastric, inferior epigastric Sides: Posterior intercostal, lumbar |
Lower end of rectum |
Superior rectal |
Middle & inferior rectal |
Posterior abdominal wall |
Splenic |
Left renal vein & other tributaries of IVC (vein of retzius) |
Bare area of liver |
Portal radicles |
Diaphragmatic |
Falciform ligament |
Paraumblical |
Diaphragmatic |
Ligamentum venosum |
Left branch of portal |
IVC via ductus venosus |
Posterior vaginal wall |
Superior rectal |
Vaginal venous plexus |
CLINICAL SIGNIFICANCE:
-
Portal hypertension
- Increased blood pressure in the portal vein i.e. elevation of the hepatic venous pressure gradient (HVPG) to >5 mmHg & pressure >10-12mm Hg called portal hypertension, is a major complication of liver disease, most commonly cirrhosis. Normal pressure is 5-10 mm Hg.
- Portal hypertension is caused by a combination of two simultaneously occurring hemodynamic processes.
- Signs of portal hypertension include those of chronic liver disease: ascites, esophageal varices, spider nevi, caput medusae, and palmar erythema.
2. Pylephlebitis
- Pylephlebitis is infection of the portal vein, usually arising from an infectious intraabdominal process such as diverticulosis.
- Portal vein provides 80% blood supplies to Liver.
- Portal Vein is formed by the union of superior mesenteric vein and the splenic vein.
- The whole hepatic portal system is valveless
- The Normal Portal venous pressure is 5-10mm Hg
- Portal hypertension is defined as the elevation of the hepatic venous pressure gradient (HVPG) to >5 mmHg.
- Left gastric vein drains into portal vein.
- Portal vein begins at L2 level.
- Two capillary beds connected by a larger blood vessel characterizes a portal system of blood vessels.
- Portal vein is Situated deep to the hepatic artery and cystic duct
- Portal circulation is also seen in an endocrine gland i.e. hypophysis cerebri
- Veins draining into portal vein are Splenic vein, Superior mesenteric vein, Inferior mesenteric vein, Gastric veins, Cystic vein.
- Portal hypertension is present if, portal venous pressure is more than 10-12mm Hg.
- Portal triad in liver is formed by Hepatic artery, Bile duct, Portal vein.