Question
Amatoxins in poisoning due to food item shown in the picture below acts by inhibiting which among the followings?
| A. |
DNA.
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| B. |
mRNA.
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| C. |
Adenosine.
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| D. |
G-proteins.
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Show Answer
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Correct Answer � B
Explanation
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|
Ans:B.) mRNA.
Amatoxin in Mushroom poisoning
- Amatoxins, which are responsible for more than 95% of mushroom-related fatalities in the United States, are cyclic octapeptides.
- At least 5 subtypes of amatoxins are known, the only significant human toxin being alpha-amatoxin, which inhibits RNA polymerase II and protein synthesis.
- Amatoxins are Hepatotoxic.
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