Question
The drug shown in the picture below
is metabolized by?
| A. |
Acetylation.
|
| B. |
Oxidation.
|
| C. |
Reduction.
|
| D. |
Hydrolysis.
|
Show Answer
|
Correct Answer � A
Explanation
|
|
Ans:A.)Acetylation.
The drug shown in the picture above is Isoniazid which is metabolized by Acetylation.
Isoniazid is extensively metabolized in liver .Most important pathway being N – acetylation
The acetylated metabolite is excreted in urine.
Drugs metabolized by acetylation
- Sulfonamides (including dapson)
- Procainamide
- PAS
- INH
- Hydralazine
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