Question
The prenatal diagnostic procedure shown in the image can be done at which period of gestation?
| A. |
12-14 weeks
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| B. |
14-16 weeks
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| C. |
16-18 weeks
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| D. |
10-12 weeks
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Show Answer
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Correct Answer � D
Explanation
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Ans:D.)10-12 weeks
The method shown in the image: Chorionic villus sampling
Chorionic villus sampling
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It is a form of prenatal diagnosis to determine chromosomal or genetic disorders in the fetus. It entails sampling of the chorionic villus (placental tissue) and testing it for chromosomal abnormalities, usually with FISH or PCR. CVS usually takes place at 10–12 weeks’ gestation, earlier than amniocentesis or percutaneous umbilical cord blood sampling.
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It can be performed in a transcervical or transabdominal manner.
Indications:
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Abnormal first-trimester screen results
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Increased nuchal translucency or other abnormal ultrasound findings
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Family history of a chromosomal abnormality or other genetic disorder
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Parents are known carriers for a genetic disorder
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Advanced maternal age (maternal age above 35). It is associated with an increased risk of Down’s syndrome and at age 35, the risk is 1:400.
Risks
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