Question
A 5 year old girl presented with recurrent skin lesions over the body as shown in the image
following trivial trauma.What can be the most possible diagnosis?
| A. |
Dermatitis Herpetiformis
|
| B. |
Epidermolysis Bullosa
|
| C. |
Bullous Pemphigoid
|
| D. |
Pemphigous Vulgaris
|
Show Answer
|
Correct Answer � B
Explanation
|
|
Ans:B.)Epidermolysis Bullosa.
Epidermolysis Bullosa
Epidermolysis bullosa (EB) is a group of inherited bullous disorders characterized by blister formation in response to trivial mechanical trauma.
Pathophysiology:
- Epidermolysis bullosa is a family of bullous disorders caused by an absence of basement membrane components due to underlying gene mutations. Epidermolysis bullosa is classified into three major categories: (1) epidermolysis bullosa simplex (intraepidermal skin separation), (2) junctional epidermolysis bullosa (skin separation in lamina lucida or central BMZ), and (3) dystrophic epidermolysis bullosa (sublamina densa BMZ separation).
- Junctional epidermolysis bullosa: minor trauma
has caused large blisters and erosions which will heal
slowly or not at all.
-
Autosomal recessive dystrophic epidermolysis
bullosa: note large blood-filled blister. Scarring has led to
fixed deformity of the fingers and loss of nails.
Like this:
Like Loading...
