Question
Identify the cell numbered ‘3’ in this pap smear examination:
| A. |
Superficial squamous epithelial cells
|
| B. |
Intermediate squamous epithelial cells
|
| C. |
Endocervical (glandular) epithelial cell
|
| D. |
Parabasal Cell
|
Show Answer
|
Correct Answer � C
Explanation
|
|
Ans:C.)Endocervical (glandular) epithelial cell.
NORMAL PAP SMEAR
| Intermediate cell (IC) |
Single cells |
Irregular |
Blue, abundant |
Small nucleus (~ size of PMN), no nucleolus |
– |
| Superficial cell (SC) |
Single cells |
Irregular |
Red, abundant |
Small nucleus, 1/2 size of IC nucleus, no nucleolus |
– |
| Squamous metaplastic cell |
Single cells/clumps of cells |
Smooth/oviod shape |
Dense, dark blue |
2X IC nucleus, nucleolus, no membrane irreg., no chromatin changes |
DDx: HSIL, basal cell |
| Endometrial cell |
Well-circumscribed clump/ball of cells with squamoid covering cells; referred to as “exodus” pattern |
Indistinct within cluster |
Blue, small/very scant |
Small, dark, nuclear moulding, degenerative changes (chromatin clumping) |
DDx: HSIL, basal cell. |
| Glandular (endocervical) cell |
Sheets of cells with regular spacing, columnar morphology may be apparent, +/-palisading at edge of clump |
Often distict |
Blue, scant-to-moderate |
Nucleus ~ size of an IC nucleus, no membrane irreg., no chromatin changes |
DDx: endometrial cel |
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