|A.||May be an indication of skin malignancy|
May be associated with Insulin resistant diabetes mellitus
Commonly occurs in lean and thin.
Ans:C. May be associated with Insulin resistant diabetes mellitus
Acanthosis nigricans is associated with obesity and insulin resistance in the majority of the patients.
Acanthosis is diffuse epidermal hyperplasia (thickening of the skin).
Implies increased thickness of the Malpighian layer (stratum basale and stratum spinosum).
Occurs primarily in flexural areas as velvety hyperpigmentation.
Commonly seen in the axilla.
Maybe a reflection of endocrinopathy such as acromegaly, Cushing’s syndrome, polycystic ovarian syndrome & GIT malignancy.