Ethylene Glycol antidote is ‑
Ans. is ‘d’ i.e., Fomepizole
The antidote for ethylene glycol poisoning is fomepizole.
- Ethylene glycol poisoning causes metabolic acidosis and renal failure and may cause death. The standard treatment is inhibition of alcohol dehydrogenase with ethanol, given in intoxicating doses, and adjunctive hemodialysis.
- Fomepizole, a new inhibitor of alcohol dehydrogenase is very effective in the treatment of ethylene glycol poisoning.
- The plasma concentration of glycolate and the urinary excretion of oxalate, the major metabolites of ethylene glycol, fall after the initiation of fomepizole therapy.