Question
Which amino acid deficiency results in the condition shown in the following image:
| A. |
Tryptophan
|
| B. |
Alanine
|
| C. |
Cysteine
|
| D. |
Histidine
|
Show Answer
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Correct Answer � A
Explanation
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|
Answer- A. Tryptophan
* Primary pellagra is caused by diets low in niacin or tryptophan.
- Pellagra is caused by the deficiency of Tryptophan as well as Niacin.
- Pellagra is seen more in women; this may be because tryptophan metabolism is inhibited by estrogen metabolites.
- Clinical features are: Dermatitis, Diarrhea and Dementia.
- Ataxia and spasticity are also seen.
* Secondary pellagra occurs when your body can’t absorb niacin.
Things that can prevent your body from absorbing niacin include:
* Alcoholism
* Eating disorders, Certain medications, including anticonvulsants and immunosuppressive drugs
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