A 59-year-old female alcoholic is brought to the emergency room with fever and foul-smelling breath. The patient subsequently develops acute bronchopneumonia and dies of respiratory insufficiency. A pulmonary abscess is identified at autopsy is shown in the image. Histologic examination of the wall of this lesion would most likely demonstrate which of the following pathologic changes?
- When the rate of dissolution of the necrotic cells is faster than the rate of repair, the resulting morphologic appearance is termed liquefactive necrosis.
- The polymorphonuclear leukocytes of the acute inflammatory reaction are endowed with potent hydrolases that are capable of digesting dead cells.
- A sharply localized collection of these acute inflammatory cells in response to a bacterial infection produces rapid death and dissolution of tissue.
- The result is often an abscess defined as a cavity formed by liquefactive necrosis in solid tissue. Caseous necrosis (choice A) is seen in necrotizing granulomas.
- In coagulative necrosis, the outline of the cell is retained. Fat is not present in the lung parenchyma. Fibrinoid necrosis is seen in patients with necrotizing vasculitis.