MCQ – 86537

Question

An investigator is comparing DNA replication in prokaryotes and eukaryotes. He finds that the entire genome of E. coli (4 × 106 base pairs) is replicated in approximately 30 minutes. A mammalian genome (3 × 109 base pairs) is usually replicated within 3 hours. Which of the following characteristics of eukaryotic DNA replication is the most accurate explanation for this finding:

A.

Absence of telomerase enzyme activity

B.

Replication inhibition at the checkpoint

C.

Simultaneous replication at multiple origins

D.

Lack of noncoding regions in DNA

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