Which organism produces a potent exotoxin?
Ans.B. Shigella dysenteriae
- The severe diarrhoea and profound dehydration which characterize S. dysenteriae infection is due largely to the effect of a heat stable, protein exotoxin lethal to intestinal epithelial cells. Early literature described it as a “neurotoxin”.
- The other species do not produce an exotoxin but possess the common ability to penetrate epithelial cells and to release endotoxin on lysis.