Question
Felty’s syndrome is associated with disease of:
| A. |
Thyrotoxicosis
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| B. |
Splenomegaly
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| C. |
Hepatomegaly
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| D. |
All of the above
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Show Answer
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Correct Answer � B
Explanation
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Ans.B. Splenomegaly
- Felty’s syndrome is the association of splenomegaly and neutropenia with rheumatoid arthritis (RA) which occurs in
- Felty syndrome is usually described as associated with or a complication of rheumatoid arthritis.
- This disorder is generally defined by the presence of three conditions: rheumatoid arthritis (RA), an enlarged spleen (spenomelgaly) and a low white blood cell count (neutropenia).
- The presence of RA gives rise to painful, stiff and swollen joints.
- A low white blood cell count, especially when accompanied by an abnormally large spleen, leads to a greater chance for infections.
- Other symptoms associated with Felty syndrome may include fatigue, fever, weight loss, and/or discoloration of patches of skin (brown pigmentation).
- The exact cause of Felty syndrome is unknown.
- It is believed to be an autoimmune disorder that may be genetically transmitted as an autosomal dominant trait.
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