Question
An 80-year-old man with long-standing diabetes and systemic hypertension dies of congestive heart failure. The luminal surface of the abdominal aorta is shown in the image. Which of the following pathologic changes would you expect to see on microscopic examination?
| A. |
Acute inflammation of the vessel wall
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| B. |
Cystic medial necrosis
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| C. |
Bacterial colonies in the vessel wall
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| D. |
Lipid deposition and smooth muscle cell hyperplasia
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Show Answer
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Correct Answer � D
Explanation
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Answer 😀 Lipid deposition and smooth muscle cell hyperplasia
Atherosclerosis is a disease of large and medium- sized elastic and muscular arteries that results in the progressive accumulation within the intima of inflammatory cells, hyperplastic smooth muscle cells, lipids, and connective tissue.
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The resulting characteristic lesion, the lipid plaque (atheroma), contains pools of extracellular lipid and numerous lipid-laden macrophages (foam cells).
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It is not an acute inflammatory or infectious process. Obliterative endarteritis is a syphilitic lesion.
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