MCQ – 87798


A 45-year-old woman complains that her fingers feel stiff. On physical examination the skin of the patient’s face appears tense and radial furrows are evident around the mouth. Laboratory studies establish a diagnosis of scleroderma. Several years later, the patient subsequently develops renal insufficiency. A renal biopsy is shown in the image. Which of the following

best describes the pathogenesis of renal vascular involvement in this patient with progressive systemic sclerosis?


Accelerated atherosclerosis


Subintimal fibromuscular thickening


Organization of microthrombi

D. Cystic medial necrosis

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