Answer: B) Herpes simplex
Explanation: A granulomatous reaction to Descemet membrane (including multinucleated giant cells) (Figs. 7-21 and 7-22) is most frequently seen with disciform keratitis with a history of herpes simplex or herpes zoster keratitis. This peculiar reaction to Descemet membrane may be related to an altered antigenicity of the membrane and subsequent development of an autosensitivity reaction. This reaction is very uncommon with other etiologic agents.