Question
A patient’s medication list includes drug X. He is going to undergo a combined trabeculectomy and cataract extraction under general anesthesia. The anesthesiologist is hesitant to use succinylcholine in view of a potential drug interaction. What could drug X be?
| A. |
Levobunolol
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| B. |
Carbachol
|
| C. |
Echothiophate iodide (phospholine iodide)
|
| D. |
Apraclonidine
|
Show Answer
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Correct Answer � C
Explanation
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|
Answer:C) Echothiophate iodide (phospholine iodide)
Explanation:Succinylcholine is a depolarizing agent (acetylcholine receptor agonist) used in anesthesia to induce short-term muscle paralysis. Echothiophate iodide is an irreversible cholinesterase inhibitor whose effects may persist for days after discontinuation of the drug. Its use could prevent succinylcholine from being metabolized, leading to prolonged respiratory paralysis. Levobunolol is a nonselective β-blocker. Carbachol is a direct-acting cholinergic. Apraclonidine is an α2 selective agonist.
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