Question
A 36-year-old woman presents with a pigmented lesion on the posterior aspect of her left calf as shown in the image). An excisional biopsy demonstrates a superficial spreading type of melanoma. Which of the following histologic features has the most important prognostic value in your evaluation of this patient?
| A. |
Degree of melanocytic atypia
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| B. |
Degree of vascularity
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| C. |
Depth of dermal invasion
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| D. |
Extent of intraepidermal invasion by melanoma cells
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Show Answer
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Correct Answer � C
Explanation
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Correct answer :c
The condition described in question is melanoma.
Melanoma, also redundantly known as malignant melanoma, is a type of skin cancer that develops from the pigment-producing cells known as melanocytes.
Melanomas typically occur in the skin but may rarely occur in the mouth, intestines or eye
Although choices A, B, and D may be factors in melanoma aggressiveness, the evaluation of tumor thickness is recognized as the single strongest prognostic variable for melanoma.
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