Question
A 60-year-old former lifeguard presents with several small, pearly nodules on the back of her neck. A biopsy of one of the nodules as shown in the image reveals buds of atypical, deeply-basophilic keratinocytes extending from the overlying epidermis into the papillary dermis. Which of the following is the appropriate diagnosis?
| A. |
Basal cell carcinoma
|
| B. |
Fibroepithelial polyp
|
| C. |
Keratoacanthoma
|
| D. |
Squamous cell carcinoma
|
Show Answer
|
Correct Answer � A
Explanation
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|
Correct answer : a
The condition described in the question is basal cell carcinoma.
BCC is the most common malignant tumor in persons with pale skin.
Although it may be locally aggressive, metastases are exceedingly rare.
BCC usually develops on the sun-damaged skin of people with fair skin and freckles.
The tumor is composed of nests of deeply basophilic epithelial cells with narrow rims of cytoplasm that are attached to the epidermis and protrude into the subjacent papillary dermis.
Basaloid keratinocytes are rarely seen in squamous cell carcinoma and are not
encountered in the other choices.
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