MCQ – 88597


96. An 20-year-old man moves from sea level to an elevation of 2,600 m to train as a skier. The increased requirement for oxygen delivery to tissues at the higher elevation stimulates the synthesis of a renal hormone (erythropoietin), which targets hematopoietic stem cells in the bone marrow. Erythropoietin promotes the survival of early erythroid progenitor cells primarily through which of the following mechanisms?

A. Altered cell-matrix adhesion


Downregulation of p53


Enhanced glucose uptake


Inhibition of apoptosis

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