Question
96. An 20-year-old man moves from sea level to an elevation of 2,600 m to train as a skier. The increased requirement for oxygen delivery to tissues at the higher elevation stimulates the synthesis of a renal hormone (erythropoietin), which targets hematopoietic stem cells in the bone marrow. Erythropoietin promotes the survival of early erythroid progenitor cells primarily through which of the following mechanisms?
A. | Altered cell-matrix adhesion |
B. |
Downregulation of p53 |
C. |
Enhanced glucose uptake |
D. |
Inhibition of apoptosis |
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