Question
A 45 year old male patient developed bullae without erythema on elbows, knee and sacral area f/b crust formation, scarring and milia. He had no photosensitivity and negative family history for bullous diseases. On DIF IgG deposition at DEJ with no blood vessel involvement is seen probable diagnosis is:
| A. |
EB dystrophic
|
| B. |
EB acquisita
|
| C. |
Porphyria CT
|
| D. |
Pemphigoid bullous
|
Show Answer
[ads id=”53026″]
|
Correct Answer � B
Explanation
|
|
Correct answer : b
Epidermolysis bullosa acquisita:
Subepidermal blistering disorder defined by autoantibodies against Non Collagenous -1(NC1) domain of collagen VII.
Clinical features :
Age of onset 44-55 years
2 forms :
Classic / mechanobullous form Ð resembles EBD
Inflammatory variant Ð resembles bullous pemphigoid (BP)
Investigation : Subepidermal blister on histology , DIF IgG deposition at DEJ.
Like this:
Like Loading...
