A 67-year-old man presents with chest wall pain and chronic nonproductive cough. A chest X-ray reveals a pleural-based mass and a large pleural effusion. A sputum sample is shown in the image. Fluid obtained from the left pleural cavity shows numerous single and clustered neoplastic cells. Which of the following is the most likely diagnosis?
Squamous cell carcinoma
Answer : C Mesothelioma
The sputum sample shows a ferruginous body, which appears as a yellow, beaded structures with clubbed ends.
Also termed asbestos bodies, they are formed by the precipitation of iron and protein complexes on asbestos fibers.
Asbestos exposure is a well-known risk factor for the development of mesothelioma.
The other choices are not associated with asbestos exposure.