Question
A 21-year-old woman is suspected of having mycoplasma pneumonia based on symptoms of a dry cough, fever, normal lung examination but abnormal chest x-ray with bilateral infiltrates. She is also anemic with hemoglobin of 10.5 g/dL, reticulocyte count of 7%, and WBC 12,000/mL. Hemolytic anemia from cold agglutinins is suspected as the cause. Which of the following tests will confirm autoimmune causation as the cause of the anemia?
| A. |
positive antinuclear antibody (ANA) |
| B. |
positive rheumatoid factor |
| C. |
polyclonal gammopathy |
| D. |
positive Coombs’ test |
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