Question
A 78-year-old man comes to the physician because of a change in his voice. His wife says his voice has progressively become higher pitched, and he has had a 5.4-kg (11.9-lb) weight loss over the past 4 months. He has smoked half a pack of cigarettes daily for the past 40 years. Direct laryngoscopy shows an irregular, nodular glottic mass. A biopsy specimen of the mass shows poorly differentiated squamous cells with nuclear atypia, hyperkeratosis, and disruption of the basement membrane. Involvement of a muscle derived from which of the following branchial arches is the most likely cause of his symptoms?
A. | 1st arch |
B. |
2nd arch |
C. |
3rd arch |
D. |
4th arch |
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