Question
A 26-year-old woman with a history of bitemporal hemianopsia and diabetes insipidus develops meningococcal infection and dies of septic shock. Examination of the brain at autopsy reveals a large cystic tumor mass replacing the midline structures in the region of the hypothalamus as shown in the image. This tumor is derived from epithelial cells originating in which of the following embryonic structures?
| A. |
Diencephalon
|
| B. |
Mesencephalon
|
| C. |
Nasopharynx
|
| D. |
Prosencephalon
|
Show Answer
|
Correct Answer � C
Explanation
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|
Answer : C Nasopharynx
Condition described in the question is craniopharyngioma
Craniopharyngiomas are solid and cystic lesions located above the sella turcica that arise from the epithelium of Rathke pouch.
This structure is a part of the embryonic nasopharynx that migrates cephalad and gives origin to the anterior lobe of the hypophysis.
Some cystic lesions are lined by squamous epithelium, whereas others, referred to as adamantinomas, are solid and resemble tumors
of dentigerous origin.
Neoplasms derived from ectopic tissues compress adjacent structures. Craniopharyngiomas generally become symptomatic in the first two decades of life, creating visual deficits and headaches.
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