Question
A 3-year-old girl is brought to the physician by her parents because of a barking cough, a raspy voice, and noisy breathing for the last 3 days. Five days ago, she had a low-grade fever and runny nose. She attends daycare. Her immunizations are up-to-date. Her temperature is 37.8°C (100°F) and respirations are 33/min. Physical examination shows supraclavicular retractions. There is a high-pitched sound present on inspiration. Examination of the throat shows erythema without exudates. Which of the following is the most likely location of the anatomic narrowing causing this patient’s symptoms?
A. |
Subglottic larynx
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B. |
Bronchioles
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C. |
Pharynx
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D. |
Epiglottis
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Show Answer
Correct Answer � A
Explanation
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Answer A) Subglottic larynx
A chest x-ray of this patient would most likely reveal a steeple sign.
Subglottic larynx
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Croup, the most likely diagnosis in this patient, is characterized by inflammation and narrowing of the subglottic part of the larynx (below the vocal folds).
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The cricoid cartilage ring of the subglottis cannot expand.
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Given the small size and floppiness of the larynx and trachea in children, mucosal swelling quickly causes hoarseness, barking cough, and inspiratory stridor.
Bronchioles
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Inflammation of the bronchioles (e.g., bronchiolitis) can also present with symptoms of upper respiratory tract infection (e.g., low-grade fever, rhinorrhea, cough).
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Narrowing of the terminal bronchioles due to edema and excessive mucus causes wheezing and crackles.
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Hoarseness and inspiratory stridor do not occur. In addition, bronchiolitis most commonly affects children < 2 years.
Pharynx
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Inflammation of the pharynx (e.g., strep throat) typically presents with erythema and exudates of the pharynx and tonsils.
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Patients primarily develop sore throat and dysphagia.
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Cervical lymphadenopathy is also a typical finding.
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Hoarseness and barking cough do not occur.
Epiglottis
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Inflammation of the epiglottis (e.g., as seen in epiglottitis) can also present with inspiratory stridor.
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Edema of the small and flaccid epiglottic cartilage in children quickly results in drooling, sore throat, dysphagia, and muffled voice, rather than hoarseness and a barking cough.
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Children with epiglottitis typically have a toxic appearance (e.g., respiratory distress, cyanosis, inspiratory retractions, restlessness) and are at high risk of developing respiratory distress.
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