Question
A patient with symptomatic pulmonary sarcoidosis is referred to discuss treatment options. Which of the following is the most appropriate initial option to prevent pulmonary fibrosis?
| A. |
Cyclophosphamide
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| B. |
Systemic corticosteroids
|
| C. |
Chest irradiation
|
| D. |
Immunoglobulins
|
Show Answer
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Correct Answer � B
Explanation
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|
Ans. B
In symptomatic patients with sarcoidosis, glucocorticoid administration is aimed at the prevention of pulmonary fibrosis.
The course of treatment is usually 3 to 6 months, but many patients do not tolerate the side effects.
Inhaled corticosteroids have been tried but results have been variable.
Other drugs to treat sarcoid include methotrexate, chloroquine, and cyclophosphamide
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