Question
A 60-year-old male develops fever and axillary lymphadenopathy. A lymph node biopsy was performed showing a sheet-like infiltrate of neoplastic cells, some of which are large and shaped like horseshoes. ALK immunohistochemistry is pending. Which of the following statements about this disorder are true?
| A. |
The cells have a patchy positivity for CD30 |
| B. | The disease usually involves lymph nodes and affects females more commonly than males |
| C. |
This entity is a type of T-cell lymphoma |
| D. |
Fluorescent in-situ hybridization (FISH) studies for ALK rearrangement should be performed regardless if immunohistochemistry for ALK is negative |
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