Question
A patient diagnosed is diagnosed with diabetes insipidus. Appropriate fluids are started. Which of the following medications is given?
| A. |
Glipizide 10 mg intravenously, daily
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| B. |
Glipizide 10 mg by mouth, daily
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| C. |
Vasopressin 10 units intravenously, daily
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| D. |
Vasopressin 5-10 units intramuscularly or subcutaneously, every 8 to 12 hours
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Show Answer
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Correct Answer � D
Explanation
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Ans. d. Vasopressin 5-10 units intramuscularly or subcutaneously, every 8 to 12 hours
Vasopressin is an antidiuretic hormone replacement drug. It may be given intramuscularly, subcutaneously, and nasally to treat diabetes insipidus, a disorder of the pituitary gland. Adult dosing is 5 to 10 units intramuscularly or subcutaneously every 8 to 12 hours in acute management of diabetes insipidus.
Pediatric dosing is 2.5 to 10 units intramuscularly, subcutaneously, or intranasally every 8 to 12 hours. The dose is titrated based on serum sodium and osmolarity, urine output, and overall fluid balance in both adults and pediatric clients.
Normally, the hypothalamus produces an antidiuretic hormone, which accumulates in the posterior pituitary.
Glipizide is a therapy for diabetes mellitus, not diabetes insipidus.
Vasopressin is not given intravenously.
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