Question
A 68-year-old male patient presented with fever, night sweats, and weight loss for 2 months. Upon clinical examination, non-tender, rubbery lymph nodes were palpable in the supraclavicular and inguinal regions on both sides. Biopsy results indicated the presence of Reed-Sternberg cells and a background infiltrate of reactive cells having been diagnosed. According to Ann Arbor Staging, this patient is categorized as
| A. |
Stage II A
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| B. |
Stage II B
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| C. |
Stage III A
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| D. |
Stage III B
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Show Answer
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Correct Answer � D
Explanation
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Ans. D Stage III B
According to Ann Arbor Staging, this patient is categorized as Stage IIIB.
In this clinical perspective, lymph node regions on both sides of the diaphragm are involved (cervical and inguinal) and the patient presents with B symptoms (fever, night sweats, and weight loss), hence this patient can be categorized as Stage IIIB.
Ann Arbor Staging of Hodkin’s lymphoma
Stage I
Involvement of a single lymph node (I) or a single extra-lymphatic organ or site (IE)
Stage II
Involvement of 2 or more lymph node regions on the same side of the diaphragm (II) or localized involvement of an extra-lymphatic organ or site and 1 or more lymph node regions on the same side of the diaphragm (IIE)
Stage III
Involvement of lymph node regions on both sides of the diaphragm (III), which may be accompanied by involvement of the spleen (IIIS) or by localized involvement of an extra-lymphatic organ or site (IIIE) or both (IIISE)
Stage IV
- Diffuse or disseminated involvement of 1 or more extra-lymphatic organs or tissues with or without associated lymph node involvement
B symptoms
The absence or incidence of fever >38°C (100.4°F) for 3 consecutive days
Drenching night sweats
Unexplained loss of > 10% of body weight in the 6 months
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