Anti-Factor Xa level
Both A and B
No monitoring is required
The anticoagulant effect of Heparin can be monitored using activated partial thromboplastin time (aPTT) and Anti-Factor Xa level.
aPTT is prolonged as heparin inhibits intrinsic pathway factors.
Prothrombin time and INR are used to monitor the anticoagulant effect of warfarin (inhibits Vitamin K dependent factor II, VII, IX, X-Factor VII has the shortest half-life).
No monitoring is required with the use of low molecular weight heparin (LMWH) and Fondaparinux.